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Assessment of Inter-Laboratory Variation in the Characterization and Analysis of the Mucosal Microbiota in Crohn’s Disease and Ulcerative Colitis
BACKGROUND: In studies evaluating the microbiome, numerous factors can contribute to technical variability. These factors include DNA extraction methodology, sequencing protocols, and data analysis strategies. We sought to evaluate the impact these factors have on the results obtained when the seque...
Autores principales: | Szamosi, Jake C., Forbes, Jessica D., Copeland, Julia K., Knox, Natalie C., Shekarriz, Shahrokh, Rossi, Laura, Graham, Morag, Bonner, Christine, Guttman, David S., Van Domselaar, Gary, Surette, Michael G., Bernstein, Charles N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472644/ https://www.ncbi.nlm.nih.gov/pubmed/32973734 http://dx.doi.org/10.3389/fmicb.2020.02028 |
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