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Chelation with a twist: a bifunctional chelator to enable room temperature radiolabeling and targeted PET imaging with scandium-44
Scandium-44 has emerged as an attractive, novel PET radioisotope with ideal emission properties and half-life (t(1/2) = 3.97 h, E(mean) β(+) = 632 keV) well matched to the pharmacokinetics of small molecules, peptides and small biologics. Conjugates of the current gold-standard chelator for (44)Sc,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472660/ https://www.ncbi.nlm.nih.gov/pubmed/32953004 http://dx.doi.org/10.1039/c9sc04655k |