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Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases

Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites indispensable in the treatment of cancer or infectious diseases. Here, we provide evidence for different evolutionary pro...

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Detalles Bibliográficos
Autores principales: Götze, Sebastian, Arp, Johannes, Lackner, Gerald, Zhang, Shuaibing, Kries, Hajo, Klapper, Martin, García-Altares, María, Willing, Karsten, Günther, Markus, Stallforth, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472662/
https://www.ncbi.nlm.nih.gov/pubmed/32953002
http://dx.doi.org/10.1039/c9sc03633d