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CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA

BACKGROUND: Modification of RNAs, particularly at the terminals, is critical for various essential cell processes; for example, uridylation is implicated in tumorigenesis, proliferation, stem cell maintenance, and immune defense against viruses and retrotransposons. Ribosomal RNAs can be regulated b...

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Detalles Bibliográficos
Autores principales: Wang, Yun, Weng, Chenchun, Chen, Xiangyang, Zhou, Xufei, Huang, Xinya, Yan, Yonghong, Zhu, Chengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472701/
https://www.ncbi.nlm.nih.gov/pubmed/32887607
http://dx.doi.org/10.1186/s12915-020-00850-z