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CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of rRNA
BACKGROUND: Modification of RNAs, particularly at the terminals, is critical for various essential cell processes; for example, uridylation is implicated in tumorigenesis, proliferation, stem cell maintenance, and immune defense against viruses and retrotransposons. Ribosomal RNAs can be regulated b...
Autores principales: | Wang, Yun, Weng, Chenchun, Chen, Xiangyang, Zhou, Xufei, Huang, Xinya, Yan, Yonghong, Zhu, Chengming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472701/ https://www.ncbi.nlm.nih.gov/pubmed/32887607 http://dx.doi.org/10.1186/s12915-020-00850-z |
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