Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice

Emerging data indicate that free heme promotes inflammation in many different disease settings, including in sickle cell disease (SCD). Although free heme, proinflammatory cytokines, and cardiac hypertrophy are co-existing features of SCD, no mechanistic links between these features have been demons...

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Detalles Bibliográficos
Autores principales: Gbotosho, Oluwabukola T., Kapetanaki, Maria G., Ghosh, Samit, Villanueva, Flordeliza S., Ofori-Acquah, Solomon F., Kato, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473032/
https://www.ncbi.nlm.nih.gov/pubmed/32973791
http://dx.doi.org/10.3389/fimmu.2020.01910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473032/
https://www.ncbi.nlm.nih.gov/pubmed/32973791
http://dx.doi.org/10.3389/fimmu.2020.01910

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