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Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction via TMPRSS2 activation of membrane fusion

Diverse SARS-like coronaviruses (SL-CoVs) have been identified from bats and other animal species. Like SARS-CoV, some bat SL-CoVs, such as WIV1, also use angiotensin converting enzyme 2 (ACE2) from human and bat as entry receptor. However, whether these viruses can also use the ACE2 of other animal...

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Detalles Bibliográficos
Autores principales: Zheng, Mei, Zhao, Xuesen, Zheng, Shuangli, Chen, Danying, Du, Pengcheng, Li, Xinglin, Jiang, Dong, Guo, Ju-Tao, Zeng, Hui, Lin, Hanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473123/
https://www.ncbi.nlm.nih.gov/pubmed/32602823
http://dx.doi.org/10.1080/22221751.2020.1787797