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Synthesis, biological evaluation and toxicity of novel tetrandrine analogues

In this work, we present the design and synthesis of novel fully synthetic analogues of the bisbenzylisoquinoline tetrandrine, a molecule with numerous pharmacological properties and the potential to treat life-threatening diseases, such as viral infections and cancer. Its toxicity to liver and lung...

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Detalles Bibliográficos
Autores principales: Schütz, Ramona, Müller, Martin, Geisslinger, Franz, Vollmar, Angelika, Bartel, Karin, Bracher, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473156/
https://www.ncbi.nlm.nih.gov/pubmed/32942071
http://dx.doi.org/10.1016/j.ejmech.2020.112810