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Antibody-secreting macrophages generated using CpG-free plasmid eliminate tumor cells through antibody-dependent cellular phagocytosis

The non-viral delivery of genes into macrophages, known as hard-to-transfect cells, is a challenge. In this study, the microporation of a CpG-free and small plasmid (pCGfd-GFP) showed high transfection efficiency, sustainable transgene expression, and good cell viability in the transfections of Raw...

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Detalles Bibliográficos
Autores principales: Cha, Eun Bi, Shin, Keun Koo, Seo, Jinho, Oh, Doo-Byoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473480/
https://www.ncbi.nlm.nih.gov/pubmed/32438971
http://dx.doi.org/10.5483/BMBRep.2020.53.8.024