High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis

Background and Objective: Agranulocytosis is a rare and potentially life-threatening complication of metamizole (dipyrone) intake that is characterized by a loss of circulating neutrophil granulocytes. While the mechanism underlying this adverse drug reaction is not well understood, involvement of t...

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Detalles Bibliográficos
Autores principales: Cismaru, Anca Liliana, Grimm, Livia, Rudin, Deborah, Ibañez, Luisa, Liakoni, Evangelia, Bonadies, Nicolas, Kreutz, Reinhold, Hallberg, Pär, Wadelius, Mia, Haschke, Manuel, Largiadèr, Carlo R., Amstutz, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473498/
https://www.ncbi.nlm.nih.gov/pubmed/32973882
http://dx.doi.org/10.3389/fgene.2020.00951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473498/
https://www.ncbi.nlm.nih.gov/pubmed/32973882
http://dx.doi.org/10.3389/fgene.2020.00951

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