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Elevated plasma 20S proteasome chymotrypsin-like activity is correlated with IL-8 levels and associated with an increased risk of death in glial brain tumor patients

INTRODUCTION: In cancer treatment an attempt has been made to pharmacologically regulate the proteasome functions, thus the aim was to test whether 20S proteasome chymotrypsin-like (ChT-L) activity has a role in glial brain tumors. Furthermore, we analyzed the correlation between proteasome activity...

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Detalles Bibliográficos
Autores principales: Koper-Lenkiewicz, Olga Martyna, Kamińska, Joanna, Reszeć, Joanna, Dymicka-Piekarska, Violetta, Ostrowska, Halina, Karpińska, Maria, Matowicka-Karna, Joanna, Tylicka, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473512/
https://www.ncbi.nlm.nih.gov/pubmed/32886667
http://dx.doi.org/10.1371/journal.pone.0238406