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Corneal dysfunction precedes the onset of hyperglycemia in a mouse model of diet-induced obesity

PURPOSE: The purpose of this study was to use a mouse model of diet-induced obesity to determine if corneal dysfunction begins prior to the onset of sustained hyperglycemia and if the dysfunction is ameliorated by diet reversal. METHODS: Six-week-old male C57BL/6 mice were fed a high fat diet (HFD)...

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Detalles Bibliográficos
Autores principales: Hargrave, Aubrey, Courson, Justin A., Pham, Vanna, Landry, Paul, Magadi, Sri, Shankar, Pooja, Hanlon, Sam, Das, Apoorva, Rumbaut, Rolando E., Smith, C. Wayne, Burns, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473521/
https://www.ncbi.nlm.nih.gov/pubmed/32886728
http://dx.doi.org/10.1371/journal.pone.0238750