Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences

All tRNAs are extensively modified, and modification deficiency often results in growth defects in the budding yeast Saccharomyces cerevisiae and neurological or other disorders in humans. In S. cerevisiae, lack of any of several tRNA body modifications results in rapid tRNA decay (RTD) of certain m...

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Detalles Bibliográficos
Autores principales: De Zoysa, Thareendra, Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473580/
https://www.ncbi.nlm.nih.gov/pubmed/32841241
http://dx.doi.org/10.1371/journal.pgen.1008893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473580/
https://www.ncbi.nlm.nih.gov/pubmed/32841241
http://dx.doi.org/10.1371/journal.pgen.1008893

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