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Loss of the ER membrane protein complex subunit Emc3 leads to retinal bipolar cell degeneration in aged mice

The endoplasmic reticulum (ER) membrane protein complex (EMC) is a conserved protein complex involved in inserting the transmembrane domain of membrane proteins into membranes in the ER. EMC3 is an essential component of EMC and is important for rhodopsin synthesis in photoreceptor cells. However, t...

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Detalles Bibliográficos
Autores principales: Zhu, Xiong, Qi, Xin, Yang, Yeming, Tian, Wanli, Liu, Wenjing, Jiang, Zhilin, Li, Shuzhen, Zhu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473584/
https://www.ncbi.nlm.nih.gov/pubmed/32886670
http://dx.doi.org/10.1371/journal.pone.0238435