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Functionally distinct roles for T and Tbx6 during mouse development

The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm. T-box factors are related through a shared DNA binding domain, the T-domain, and can t...

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Detalles Bibliográficos
Autores principales: Wehn, Amy K., Farkas, Deborah R., Sedlock, Carly E., Subedi, Dibya, Chapman, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473639/
https://www.ncbi.nlm.nih.gov/pubmed/32855167
http://dx.doi.org/10.1242/bio.054692