Cargando…

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

During cell division, misaligned chromosomes are captured and aligned by motors before their segregation. The CENP-E motor is recruited to polar unattached kinetochores to facilitate chromosome alignment. The spindle checkpoint protein BubR1 (also known as BUB1B) has been reported as a CENP-E intera...

Descripción completa

Detalles Bibliográficos
Autores principales: Legal, Thibault, Hayward, Daniel, Gluszek-Kustusz, Agata, Blackburn, Elizabeth A., Spanos, Christos, Rappsilber, Juri, Gruneberg, Ulrike, Welburn, Julie P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473641/
https://www.ncbi.nlm.nih.gov/pubmed/32665320
http://dx.doi.org/10.1242/jcs.246025