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The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment
During cell division, misaligned chromosomes are captured and aligned by motors before their segregation. The CENP-E motor is recruited to polar unattached kinetochores to facilitate chromosome alignment. The spindle checkpoint protein BubR1 (also known as BUB1B) has been reported as a CENP-E intera...
Autores principales: | Legal, Thibault, Hayward, Daniel, Gluszek-Kustusz, Agata, Blackburn, Elizabeth A., Spanos, Christos, Rappsilber, Juri, Gruneberg, Ulrike, Welburn, Julie P. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473641/ https://www.ncbi.nlm.nih.gov/pubmed/32665320 http://dx.doi.org/10.1242/jcs.246025 |
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