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Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1

The concentration of essential micronutrients, such as copper (used here to describe both Cu(+) and Cu(2+)), within the cell is tightly regulated to avoid their adverse deficiency and toxicity effects. Retromer-mediated sorting and recycling of nutrient transporters within the endo-lysosomal network...

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Detalles Bibliográficos
Autores principales: Curnock, Rachel, Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473646/
https://www.ncbi.nlm.nih.gov/pubmed/32843536
http://dx.doi.org/10.1242/jcs.249201