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Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1
The concentration of essential micronutrients, such as copper (used here to describe both Cu(+) and Cu(2+)), within the cell is tightly regulated to avoid their adverse deficiency and toxicity effects. Retromer-mediated sorting and recycling of nutrient transporters within the endo-lysosomal network...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473646/ https://www.ncbi.nlm.nih.gov/pubmed/32843536 http://dx.doi.org/10.1242/jcs.249201 |