suz12 inactivation in p53- and nf1-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types

Polycomb repressive complex 2 (PRC2) is an epigenetic regulator of gene expression that possesses histone methyltransferase activity. PRC2 trimethylates lysine 27 of histone H3 proteins (H3K27me3) as a chromatin modification associated with repressed transcription of genes frequently involved in cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Oppel, Felix, Ki, Dong H., Zimmerman, Mark W., Ross, Kenneth N., Tao, Ting, Shi, Hui, He, Shuning, Aster, Jon C., Look, A. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473648/
https://www.ncbi.nlm.nih.gov/pubmed/32651197
http://dx.doi.org/10.1242/dmm.042341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473648/
https://www.ncbi.nlm.nih.gov/pubmed/32651197
http://dx.doi.org/10.1242/dmm.042341

Ejemplares similares