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Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density

Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). In the wobbler mouse, a model for human motor neuron (MN) disease, reduction in the levels of Vps54 causes neurodegeneration. Howev...

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Detalles Bibliográficos
Autores principales: Patel, Prajal H., Wilkinson, Emily C., Starke, Emily L., McGimsey, Malea R., Blankenship, J. Todd, Barbee, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473652/
https://www.ncbi.nlm.nih.gov/pubmed/32747448
http://dx.doi.org/10.1242/bio.053421