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Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders
The importance of apolipoprotein E (APOE) in late-onset Alzheimer's disease (LOAD) has been firmly established, but the mechanisms through which it exerts its pathogenic effects remain elusive. In addition, the sex-dependent effects of APOE on LOAD risk and endophenotypes have yet to be explain...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473656/ https://www.ncbi.nlm.nih.gov/pubmed/32859588 http://dx.doi.org/10.1242/dmm.045211 |