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Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders

The importance of apolipoprotein E (APOE) in late-onset Alzheimer's disease (LOAD) has been firmly established, but the mechanisms through which it exerts its pathogenic effects remain elusive. In addition, the sex-dependent effects of APOE on LOAD risk and endophenotypes have yet to be explain...

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Detalles Bibliográficos
Autores principales:	Gamache, Julia, Yun, Young, Chiba-Falek, Ornit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473656/ https://www.ncbi.nlm.nih.gov/pubmed/32859588 http://dx.doi.org/10.1242/dmm.045211

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