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Live-cell imaging and analysis reveal cell phenotypic transition dynamics inherently missing in snapshot data

Recent advances in single-cell techniques catalyze an emerging field of studying how cells convert from one phenotype to another, in a step-by-step process. Two grand technical challenges, however, impede further development of the field. Fixed cell–based approaches can provide snapshots of high-dim...

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Detalles Bibliográficos
Autores principales: Wang, Weikang, Douglas, Diana, Zhang, Jingyu, Kumari, Sangeeta, Enuameh, Metewo Selase, Dai, Yan, Wallace, Callen T., Watkins, Simon C., Shu, Weiguo, Xing, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473671/
https://www.ncbi.nlm.nih.gov/pubmed/32917609
http://dx.doi.org/10.1126/sciadv.aba9319