Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain

Principal neurons encode information by varying their firing rate and patterns precisely fine-tuned through GABAergic interneurons. Dysregulation of inhibition can lead to neuropsychiatric disorders, yet little is known about the molecular basis underlying inhibitory control. Here, we find that exce...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Mei, Arsenault, Jason, Bah, Alaji, Krzeminski, Mickael, Fekete, Adam, Chao, Owen Y., Pacey, Laura K., Wang, Alex, Forman-Kay, Julie, Hampson, David R., Wang, Lu-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473840/
https://www.ncbi.nlm.nih.gov/pubmed/30224722
http://dx.doi.org/10.1038/s41380-018-0240-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473840/
https://www.ncbi.nlm.nih.gov/pubmed/30224722
http://dx.doi.org/10.1038/s41380-018-0240-0

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