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Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain
Principal neurons encode information by varying their firing rate and patterns precisely fine-tuned through GABAergic interneurons. Dysregulation of inhibition can lead to neuropsychiatric disorders, yet little is known about the molecular basis underlying inhibitory control. Here, we find that exce...
Autores principales: | Yang, Yi-Mei, Arsenault, Jason, Bah, Alaji, Krzeminski, Mickael, Fekete, Adam, Chao, Owen Y., Pacey, Laura K., Wang, Alex, Forman-Kay, Julie, Hampson, David R., Wang, Lu-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473840/ https://www.ncbi.nlm.nih.gov/pubmed/30224722 http://dx.doi.org/10.1038/s41380-018-0240-0 |
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