An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

SARS-CoV-2 enters host cells through an interaction between the spike glycoprotein and the angiotensin converting enzyme 2 (ACE2) receptor. Directly preventing this interaction presents an attractive possibility for suppressing SARS-CoV-2 replication. Here, we report the isolation and characterizati...

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Detalles Bibliográficos
Autores principales: Hanke, Leo, Vidakovics Perez, Laura, Sheward, Daniel J., Das, Hrishikesh, Schulte, Tim, Moliner-Morro, Ainhoa, Corcoran, Martin, Achour, Adnane, Karlsson Hedestam, Gunilla B., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473855/
https://www.ncbi.nlm.nih.gov/pubmed/32887876
http://dx.doi.org/10.1038/s41467-020-18174-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473855/
https://www.ncbi.nlm.nih.gov/pubmed/32887876
http://dx.doi.org/10.1038/s41467-020-18174-5

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