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Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes

Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes P450 to regulate cancer proliferation and chemoresistance. However, its physiological functions remain unknown. Herein, we demonstrate that P...

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Detalles Bibliográficos
Autores principales: Furuhata, Ryogo, Kabe, Yasuaki, Kanai, Ayaka, Sugiura, Yuki, Tsugawa, Hitoshi, Sugiyama, Eiji, Hirai, Miwa, Yamamoto, Takehiro, Koike, Ikko, Yoshikawa, Noritada, Tanaka, Hirotoshi, Koseki, Masahiro, Nakae, Jun, Matsumoto, Morio, Nakamura, Masaya, Suematsu, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473863/
https://www.ncbi.nlm.nih.gov/pubmed/32887925
http://dx.doi.org/10.1038/s42003-020-01202-x