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Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes
Progesterone receptor membrane associated component 1 (PGRMC1) exhibits haem-dependent dimerization on cell membrane and binds to EGF receptor and cytochromes P450 to regulate cancer proliferation and chemoresistance. However, its physiological functions remain unknown. Herein, we demonstrate that P...
Autores principales: | Furuhata, Ryogo, Kabe, Yasuaki, Kanai, Ayaka, Sugiura, Yuki, Tsugawa, Hitoshi, Sugiyama, Eiji, Hirai, Miwa, Yamamoto, Takehiro, Koike, Ikko, Yoshikawa, Noritada, Tanaka, Hirotoshi, Koseki, Masahiro, Nakae, Jun, Matsumoto, Morio, Nakamura, Masaya, Suematsu, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473863/ https://www.ncbi.nlm.nih.gov/pubmed/32887925 http://dx.doi.org/10.1038/s42003-020-01202-x |
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