Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy

Despite the clear association between myocardial injury, heart failure and depressed myocardial energetics, little is known about upstream signals responsible for remodeling myocardial metabolism after pathological stress. Here, we report increased mitochondrial calmodulin kinase II (CaMKII) activat...

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Detalles Bibliográficos
Autores principales: Luczak, Elizabeth D., Wu, Yuejin, Granger, Jonathan M., Joiner, Mei-ling A., Wilson, Nicholas R., Gupta, Ashish, Umapathi, Priya, Murphy, Kevin R., Reyes Gaido, Oscar E., Sabet, Amin, Corradini, Eleonora, Tseng, Wen-Wei, Wang, Yibin, Heck, Albert J. R., Wei, An-Chi, Weiss, Robert G., Anderson, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473864/
https://www.ncbi.nlm.nih.gov/pubmed/32887881
http://dx.doi.org/10.1038/s41467-020-18165-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473864/
https://www.ncbi.nlm.nih.gov/pubmed/32887881
http://dx.doi.org/10.1038/s41467-020-18165-6

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