Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

During an immune response, natural killer (NK) cells activate specific metabolic pathways to meet the increased energetic and biosynthetic demands associated with effector functions. Here, we found in vivo activation of NK cells during Listeria monocytogenes infection-augmented transcription of gene...

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Detalles Bibliográficos
Autores principales: Gerbec, Zachary J., Hashemi, Elaheh, Nanbakhsh, Arash, Holzhauer, Sandra, Yang, Chao, Mei, Ao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J., Riese, Matthew J., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474003/
https://www.ncbi.nlm.nih.gov/pubmed/32858341
http://dx.doi.org/10.1016/j.isci.2020.101454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474003/
https://www.ncbi.nlm.nih.gov/pubmed/32858341
http://dx.doi.org/10.1016/j.isci.2020.101454

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