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Identification of mycobacteriophage toxic genes reveals new features of mycobacterial physiology and morphology

Double-stranded DNA tailed bacteriophages typically code for 50–200 genes, of which 15–35 are involved in virion structure and assembly, DNA packaging, lysis, and DNA metabolism. However, vast numbers of other phage genes are small, are not required for lytic growth, and are of unknown function. The...

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Detalles Bibliográficos
Autores principales: Ko, Ching-Chung, Hatfull, Graham F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474061/
https://www.ncbi.nlm.nih.gov/pubmed/32887931
http://dx.doi.org/10.1038/s41598-020-71588-5