Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global public health. The coronavirus main protease (M(pro), also called 3CLpro) is essential for processing and maturation of the viral polyprotein, therefore recognized as an attractive drug target. Here we show that a...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Lifeng, Ye, Fei, Feng, Yong, Yu, Feng, Wang, Qisheng, Wu, Yan, Zhao, Cheng, Sun, Huan, Huang, Baoying, Niu, Peihua, Song, Hao, Shi, Yi, Li, Xuebing, Tan, Wenjie, Qi, Jianxun, Gao, George Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474075/
https://www.ncbi.nlm.nih.gov/pubmed/32887884
http://dx.doi.org/10.1038/s41467-020-18233-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474075/
https://www.ncbi.nlm.nih.gov/pubmed/32887884
http://dx.doi.org/10.1038/s41467-020-18233-x

Ejemplares similares