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Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease
COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global public health. The coronavirus main protease (M(pro), also called 3CLpro) is essential for processing and maturation of the viral polyprotein, therefore recognized as an attractive drug target. Here we show that a...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474075/ https://www.ncbi.nlm.nih.gov/pubmed/32887884 http://dx.doi.org/10.1038/s41467-020-18233-x |