Cargando…

Impact of glycan cloud on the B-cell epitope prediction of SARS-CoV-2 Spike protein

The SARS-CoV-2 outbreak originated in China in late 2019 and has since spread to pandemic proportions. Diagnostics, therapeutics and vaccines are urgently needed. We model the trimeric Spike protein, including flexible loops and all N-glycosylation sites, in order to elucidate accessible epitopes fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wintjens, René, Bifani, Amanda Makha, Bifani, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474083/
https://www.ncbi.nlm.nih.gov/pubmed/32944295
http://dx.doi.org/10.1038/s41541-020-00237-9