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Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction

Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic cause of myocardial infarction (MI), typically in young women. We undertook a genome-wide association study of SCAD (N(cases) = 270/N(controls) = 5,263) and identified and replicated an association of rs12740679 at chromosome 1q2...

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Detalles Bibliográficos
Autores principales: Saw, Jacqueline, Yang, Min-Lee, Trinder, Mark, Tcheandjieu, Catherine, Xu, Chang, Starovoytov, Andrew, Birt, Isabelle, Mathis, Michael R., Hunker, Kristina L., Schmidt, Ellen M., Jackson, Linda, Fendrikova-Mahlay, Natalia, Zawistowski, Matthew, Brummett, Chad M., Zoellner, Sebastian, Katz, Alexander, Coleman, Dawn M., Swan, Kirby, O’Donnell, Christopher J., Zhou, Xiang, Li, Jun Z., Gornik, Heather L., Assimes, Themistocles L., Stanley, James C., Brunham, Liam R., Ganesh, Santhi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474092/
https://www.ncbi.nlm.nih.gov/pubmed/32887874
http://dx.doi.org/10.1038/s41467-020-17558-x