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Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction
Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic cause of myocardial infarction (MI), typically in young women. We undertook a genome-wide association study of SCAD (N(cases) = 270/N(controls) = 5,263) and identified and replicated an association of rs12740679 at chromosome 1q2...
Autores principales: | Saw, Jacqueline, Yang, Min-Lee, Trinder, Mark, Tcheandjieu, Catherine, Xu, Chang, Starovoytov, Andrew, Birt, Isabelle, Mathis, Michael R., Hunker, Kristina L., Schmidt, Ellen M., Jackson, Linda, Fendrikova-Mahlay, Natalia, Zawistowski, Matthew, Brummett, Chad M., Zoellner, Sebastian, Katz, Alexander, Coleman, Dawn M., Swan, Kirby, O’Donnell, Christopher J., Zhou, Xiang, Li, Jun Z., Gornik, Heather L., Assimes, Themistocles L., Stanley, James C., Brunham, Liam R., Ganesh, Santhi K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474092/ https://www.ncbi.nlm.nih.gov/pubmed/32887874 http://dx.doi.org/10.1038/s41467-020-17558-x |
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