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Identification of impurities in nafamostat mesylate using HPLC-IT-TOF/MS: A series of double-charged ions

Nafamostat mesylate is a serine protease inhibitor used in the treatment of acute pancreatitis. The impurities in nafamostat mesylate, the active pharmaceutical ingredient (API), were profiled via high performance liquid chromatography tandem ion trap coupled with time-of-flight mass spectrometer (H...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxin, An, Lufan, Zhang, Lin, Wang, Rulin, Tian, Yuan, Zhang, Zunjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474109/
https://www.ncbi.nlm.nih.gov/pubmed/32923008
http://dx.doi.org/10.1016/j.jpha.2020.03.002