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Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C-1305()
5-Dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) is a promising antitumor compound developed in our laboratory. A better understanding of its metabolic transformations is still needed to explain the multidirectional mechanism of pharmacological action of triazoloacridinone derivatives...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474135/ https://www.ncbi.nlm.nih.gov/pubmed/32923012 http://dx.doi.org/10.1016/j.jpha.2020.03.011 |