Norepinephrine Has Dual Effects on Human Colonic Contractions Through Distinct Subtypes of Alpha 1 Adrenoceptors

BACKGROUND & AIMS: Colonic musculature contain smooth muscle cells (SMC), interstitial cells of Cajal (ICC), and platelet-derived growth factor receptor α(+) cells (PDGFRα(+) cells), which are electrically coupled and operate together as the SIP syncytium. PDGFRα(+) cells have enriched expressio...

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Detalles Bibliográficos
Autores principales: Kurahashi, Masaaki, Kito, Yoshihiko, Hara, Masayasu, Takeyama, Hiromitsu, Sanders, Kenton M., Hashitani, Hikaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474159/
https://www.ncbi.nlm.nih.gov/pubmed/32376421
http://dx.doi.org/10.1016/j.jcmgh.2020.04.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474159/
https://www.ncbi.nlm.nih.gov/pubmed/32376421
http://dx.doi.org/10.1016/j.jcmgh.2020.04.015

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