Crystallographic evidence for unintended benziso­thia­zolinone 1-oxide formation from benzo­thia­zinones through oxidation

1,3-Benzo­thia­zin-4-ones (BTZs) are a promising new class of drugs with activity against Mycobacterium tuberculosis, which have already reached clinical trials. A product obtained in low yield upon treatment of 8-nitro-2-(piperidin-1-yl)-6-(tri­fluoro­meth­yl)-4H-benzo­thia­zin-4-one with 3-chloro­...

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Detalles Bibliográficos
Autores principales: Eckhardt, Tamira, Goddard, Richard, Lehmann, Christoph, Richter, Adrian, Sahile, Henok Asfaw, Liu, Rui, Tiwari, Rohit, Oliver, Allen G., Miller, Marvin J., Seidel, Rüdiger W., Imming, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474187/
https://www.ncbi.nlm.nih.gov/pubmed/32887862
http://dx.doi.org/10.1107/S2053229620010931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474187/
https://www.ncbi.nlm.nih.gov/pubmed/32887862
http://dx.doi.org/10.1107/S2053229620010931

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