Cargando…
Mechanical Unfolding of Proteins—A Comparative Nonequilibrium Molecular Dynamics Study
Mechanical signals regulate functions of mechanosensitive proteins by inducing structural changes that are determinant for force-dependent interactions. Talin is a focal adhesion protein that is known to extend under mechanical load, and it has been shown to unfold via intermediate states. Here, we...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474207/ https://www.ncbi.nlm.nih.gov/pubmed/32822586 http://dx.doi.org/10.1016/j.bpj.2020.07.030 |