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The Effects of O(6)-methyl Guanine DNA-methyl Transferase Promotor Methylation and CpG1, CpG2, CpG3 and CpG4 Methylation on Treatment Response and their Prognostic Significance in Patients with Glioblastoma

This retrospective study examined the prognostic significance and treatment effect of promoter methylation of O(6)- methyl guanine methyl transferase (MGMT) and meth-ylation of CpG 1, CpG2, CpG3 and CpG4 in glioblastoma (GB) patients received postoperative radiotherapy (PORT), with or without adjuva...

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Detalles Bibliográficos
Autores principales: Yildiz, OG, Aslan, D, Akalin, H, Erdem, Y, Canoz, O, Aytekin, A, Ozoner, S, Dundar, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474218/
https://www.ncbi.nlm.nih.gov/pubmed/32953407
http://dx.doi.org/10.2478/bjmg-2020-0015