The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development

The retinal ganglion cell (RGC) competence factor ATOH7 is dynamically expressed during retinal histogenesis. ATOH7 transcription is controlled by a promoter-adjacent primary enhancer and a remote shadow enhancer (SE). Deletion of the ATOH7 human SE causes nonsyndromic congenital retinal nonattachme...

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Detalles Bibliográficos
Autores principales: Miesfeld, Joel B., Ghiasvand, Noor M., Marsh-Armstrong, Brennan, Marsh-Armstrong, Nicholas, Miller, Eric B., Zhang, Pengfei, Manna, Suman K., Zawadzki, Robert J., Brown, Nadean L., Glaser, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474671/
https://www.ncbi.nlm.nih.gov/pubmed/32817515
http://dx.doi.org/10.1073/pnas.2006888117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474671/
https://www.ncbi.nlm.nih.gov/pubmed/32817515
http://dx.doi.org/10.1073/pnas.2006888117

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