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Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws

Introduction of exogenous genetic material into primary stem cells is essential for studying biological function and for clinical applications. Traditional delivery methods for nucleic acids, such as electroporation, have advanced the field, but have negative effects on stem cell function and viabil...

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Detalles Bibliográficos
Autores principales: Schmiderer, Ludwig, Subramaniam, Agatheeswaran, Žemaitis, Kristijonas, Bäckström, Alexandra, Yudovich, David, Soboleva, Svetlana, Galeev, Roman, Prinz, Christelle N., Larsson, Jonas, Hjort, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474688/
https://www.ncbi.nlm.nih.gov/pubmed/32817519
http://dx.doi.org/10.1073/pnas.2001367117