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Membrane-tethering of cytochrome c accelerates regulated cell death in yeast

Intrinsic apoptosis as a modality of regulated cell death is intimately linked to permeabilization of the outer mitochondrial membrane and subsequent release of the protein cytochrome c into the cytosol, where it can participate in caspase activation via apoptosome formation. Interestingly, cytochro...

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Detalles Bibliográficos
Autores principales: Toth, Alexandra, Aufschnaiter, Andreas, Fedotovskaya, Olga, Dawitz, Hannah, Ädelroth, Pia, Büttner, Sabrina, Ott, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474732/
https://www.ncbi.nlm.nih.gov/pubmed/32892209
http://dx.doi.org/10.1038/s41419-020-02920-0