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Inhibited CSF1R Alleviates Ischemia Injury via Inhibition of Microglia M1 Polarization and NLRP3 Pathway

Ischemia cerebral stroke is one of the common neurological diseases with severe inflammatory response and neuron death. The inhibition of colony-stimulating factor 1 receptor (CSF1R) which especially expressed in microglia/macrophage exerted neuroprotection in stroke. However, the underlying neuroin...

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Detalles Bibliográficos
Autores principales: Du, Xiaoxue, Xu, Yuzhen, Chen, Shijia, Fang, Marong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474788/
https://www.ncbi.nlm.nih.gov/pubmed/32908485
http://dx.doi.org/10.1155/2020/8825954