Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer

Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with challenges regarding the initiation and advancement of the disease. The growth of tumor cells is accompanied by mutations in nuclear and in mitochondrial genomes. Thus, mitochondrial DNA mutations may be used as...

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Detalles Bibliográficos
Autores principales: Arstad, Christian, Taskén, Kristin, Refinetti, Paulo, Axcrona, Ulrika, Giercksky, Karl-Erik, Ekstrøm, Per Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474793/
https://www.ncbi.nlm.nih.gov/pubmed/32908706
http://dx.doi.org/10.1155/2020/7673684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474793/
https://www.ncbi.nlm.nih.gov/pubmed/32908706
http://dx.doi.org/10.1155/2020/7673684

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