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G-quadruplex stabilization in the ions and maltose transporters gene inhibit Salmonella enterica growth and virulence

The G-quadruplex structure is a highly conserved drug target for preventing infection of several human pathogens. We tried to explore G-quadruplex forming motifs as promising drug targets in the genome of Salmonella enterica that causes enteric fever in humans. Herein, we report three highly conserv...

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Detalles Bibliográficos
Autores principales: Jain, Neha, Mishra, Subodh Kumar, Shankar, Uma, Jaiswal, Ankit, Sharma, Tarun Kumar, Kodgire, Prashant, Kumar, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474834/
https://www.ncbi.nlm.nih.gov/pubmed/32898642
http://dx.doi.org/10.1016/j.ygeno.2020.09.010