Pharmacophore-driven identification of N-methyl-D-receptor antagonists as potent neuroprotective agents validated using in vivo studies

Alzheimer’s disease (AD), apparently the most widespread reason behind dementia, is delineated by a continuous cognitive weakening in the aged. During its progression, N-methyl-D-aspartate receptor (NMDAR) antagonists are known to play a pivotal part in the mechanisms of learning and memory. Since t...

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Detalles Bibliográficos
Autores principales: Sharma, Mukta, Mittal, Anupama, Singh, Aarti, Jainarayanan, Ashwin K, Sharma, Swapnil, Paliwal, Sarvesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474860/
https://www.ncbi.nlm.nih.gov/pubmed/32913897
http://dx.doi.org/10.1093/biomethods/bpaa013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474860/
https://www.ncbi.nlm.nih.gov/pubmed/32913897
http://dx.doi.org/10.1093/biomethods/bpaa013

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